Kisspeptin (KISS-1, Protein KISS-1, Metastin, Kp-10 peptide) – 5MG per vial

Clinical Test Expectation Kisspeptin - Human Subjects : Maintenance of normal reproductive functions, help stop the spread of cancer, principal activator of GnRH neurons, assists with onset of puberty, mood stabilizer. Strength - 5MG per vial

Introduction Kisspeptin 10 seeks to resolve a serious issue that is rarely discussed – reproductive health. There are countless people that struggle with fertility and reproductive disorders. Furthermore, even more suffer from the symptoms of sexually transmitted diseases (STDs) and other sexual malformations. Thankfully, Kisspeptin 10 promises to offer a solution.

The peptide is making noise for serving as an unconventional form of treatment for various sexual health and reproductive health issues. Even better, Kisspeptin 10 stimulates reproductive hormones in both men and women. Therefore, either sex can inherit numerous benefits from peptide therapy like Kisspeptin 10. Learn more about Kisspeptin 10 in our complete review.

Kisspeptin occurs naturally in the body. Its a protein that is generated to serve important roles in hormone signaling especially during puberty and reproduction. As a result, Kisspeptin 10 was created to replicate the effects of the natural peptide while producing several other benefits:

• Increases Testosterone
• Increases Sexual Arousal
• Improves Mood & Behavior
• Infertility Treatment
• Prevents Spreading of Cancer
• Regulates the Kidneys
• Promotes New Blood Vessels

For starters, research indicates that Kisspeptin 10 influences the Gonadotropin Releasing Hormone (GnRH). GnRH is produced and released by specialized nerve cells in the hypothalamus of the brain. Then, the hormone is released into tiny blood cells where the compound stimulates the pituitary gland. There, the peptide begins to directly influence 2 hormones critical to reproductive health:

• Follicle Stimulating Hormone (FSH)
• Luteinizing Hormone (LH)

The FSH and LH hormones are absolutely essential to reproductive functions because they act on the testes and ovaries, respectfully. For this reason, Kisspeptin 10 is effective in both male and female patients.

Benefits of Kisspeptin 10 Increases Testosterone Kisspeptin 10 has demonstrated in research to influence the circulation of the follicle stimulating hormone (FSH) and luteinizing hormone (LH). These 2 hormones are critical in sexual and reproductive health. The LH and FSH hormones directly act on the testes and ovaries which is how the peptide can stimulate fertility. On the other hand, Leydig cells generate new testosterone leading to several impressive benefits. Studies have shown that Kisspeptin 10 increases testosterone levels in mice while not disturbing normal hormones in females. Meanwhile, another study supports that K-10 peptide can offer safe and effective treatment for low testosterone. Unfortunately, testosterone levels generally decline when men age leading to low energy, fatigue, and low libido. However, Kisspeptin 10 seeks to reverse the signs of aging by stimulating increases in production that lead you to feeling younger again.

Increases Sexual Arousal Kisspeptin 10 is also outstanding at stimulating sexual arousal. Kisspeptins are regarded as a group of compounds known as neuroendocrine peptides. Neuroendocrine peptides like K-10 promote the release of Gonadotropin Releasing Hormone (GnRH). The hormone acts in the brain and therefore encourages the development of numerous sex hormones. For this reason, it’s not uncommon for Kisspeptin 10 users to notice heightened sexual energy and arousal. The boost in testosterone compliments the increase in LH levels leading to intense sexual desires. These effects are both evident on male and female users seeking a more fulfilling sex life. Therefore, Kisspeptin 10 may do wonders for low libido or erectile dysfunction (ED).

Improves Mood & Behavior Often, reproductive health is closely connected to mental and emotional health. Consequently, it’s not that surprising that powerful neuroendocrine peptides like Kisspeptin 10 influence mood and behavior. The benefits of experiencing a pleasant mood with Kisspeptin 10 revolves around an animal study. Research from the study was noteworthy concluding that K-10 enhances brain activity. The findings discovered that the peptide improved mood and increased motivation in study participants. Thus, researchers found both emotional and sexual benefits to using Kisspeptin 10. K-10 peptide may also influence anxiety and fear yet more research is necessary to reach a firm conclusion.

Infertility Treatment There is nothing more frustrating for a woman than the desire to get pregnant yet experiencing fertility issues. Unfortunately, this remains an area of medical science that experts have yet to master. It leads many to seek alternative treatments or solutions for infertility. Thankfully, there is evidence to suggest Kisspeptin 10 may influence pregnancy. The evidence is based on a clinical trial that found mice with infertility experienced restored hormone levels following Kisspeptin 10 treatment. Moreover, other research suggests that the peptide triggers ovulation. It’s a groundbreaking revelation since modern medicine would also have the ability to fertilize these eggs. There are some that even argue that Kisspeptin 10 treatment is a safer alternative than other procedures for undergoing in vitro fertilization. However, despite the promising news, more research is still needed to support using the peptide for this purpose. For now, like most peptides, individuals have no choice but to experiment with K-10 because of the lack of FDA approval. It’s unfortunate considering that recent findings also concluded that Kisspeptin 10 may prevent serious complications during pregnancy, such as miscarriage. Thus, scientists believe that monitoring kisspeptin levels early in pregnancy may avoid several complications that may occur in the future.

Lastly, since kisspeptin levels are highest during adolescent, K-10 use could treat puberty dysfunctions and other sexual malfunctions.

Prevents Spread of Cancer Kisspeptin 10 directly influences hormones in the brain. As a result, the peptide is not only influential in determining mood and behavior, but other serious conditions. For example, Kisspeptin 10 has been found to suppress tumor growth and spread. In fact, the peptide treatment was able to suppress malignant skin cancer by 95%. Researchers determined in the study that this was a result of the ability for peptides to reduce cell cancer migration. The findings were profound and led some medical experts to question if the peptide can do the same for other types of cancer. For now, research supports the use of Kisspeptin 10 for several forms of cancer treatment:

• Breast Cancer
• Ovarian Cancer
• Skin Cancer
• Prostate Cancer
• Bladder Cancer
• Gastrointestinal (GI) Cancer
• Thyroid Cancer

Despite the direct evidence that K-10 prevents the spread of cancer – the substance remains outside FDA approval.

Regulates the Kidneys The kidneys are a very unique organ that is also critical to overall health. While you are born with 2 kidneys yet only technically need 1, it’s important not to make waste of it. Consequently, it’s refreshing that K-10 peptide is linked to proper kidney function. Kisspeptin 10 increases the production of aldosterone. Aldosterone is closely connected to regulating blood pressure and kidney function. Thus, the peptide may assist those with alcohol use disorder and other health problems in the future. Finally, Kisspeptin 10 is known to assist in the breakdown of pregnenolone. The substance delivers positive and negative effects to the body yet is counter-productive to the kidney.

Promotes New Blood Vessels Angiogenesis, otherwise known as the formation of new blood vessels, is vital to cardiovascular health. Sadly, angiogenesis (like many functions of the body) deteriorates with age leading to a host of health problems. However, miracle aids in the body like peptides are capable of resurrecting natural process such as angiogenesis. Therefore, users of K-10 often report improvements related to new blood vessels. Blood vessel growth is essential with anti-aging treatment to avoid serious health risks and maintain a healthy lifestyle. Kisspeptin 10 presents rapid improvements especially when its administered via injection.  Injections enter the skin tissue and bloodstream quickly to produce immediate results. It’s often the best method to administer Kisspeptin 10 due to its shorter half-life. Peptides are extremely powerful yet also delicate which is why oral supplements like pills and nasal sprays are not considered quite as effective as injections.

Dosing Details You inject 1ml water into the vial of Kisspeptin from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in color you draw out 10 (1 unit)  on the syringe 4 times a week evenly spaced in days. Inject in the morning before breakfast and inject it into the tummy under the skin into the fatty skin layer. A vial should last 2 weeks.

How long will a vial last ? A vial should last 14 days

Clinical Test Expectation DSIP - Human Subjects : Help induce better sleep. Relieves emotional and psychological responses to stress Strength - 2MG per vial

Introduction The DSIP or the Delta sleep-inducing Peptide is a somnogeneric nonapeptide that impacts the neuromodulation. It is typically found in the brain and passes by the blood barriers quite quickly. Studies have shown that DSIP and as well as its analogs are classified as peptide neuromodulators. Studies have also shown that DSIP has exhibited a stress-protective action that helps decrease stress metabolic disorders for humans and animals.

It is believed that the Delta Sleep-Inducing Peptide works in such a way that it modulates the activity of GABAergic gluta and other neuronal systems too.

DSIP in summary :

• Help induce better sleep
• And relieve emotional and psychological responses to stress

Although, it is not recommended to give out DSIP just before going to bed. The dose should be given during the day to help improve sleep the next night and as well as several days to come.

 But you must remember that DSIP only works for short-term benefits and not for long-term management for insomnia.

Dosing Details You inject 2ml water into the vial of DSIP from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 10 – 20 (1 to 2 units) as tolerance increases , on the syringe each night before bed and inject it into the tummy under the skin into the fatty skin layer. A vial should last 10-20 days depending on dose used.

How long will a vial last ? A vial should last 10-20 days.

Clinical Test Expectation ACE-031 - Human Subjects : Massive increases in muscle mass and strength Strength - 1MG per vial

Introduction ACE-031 is a soluble form of activin receptor type IIB (ActRIIB). ACE-031 promotes muscle growth by binding to myostatin and other negative regulators of muscle mass.

The scientists are still figuring out what properties the peptide has , but we already know a number of beneficial effects of its use, including:

• acceleration of muscle gain process by blocking myostatin hormone;
• fat-burning effect. ACE-031 reduces the amount of leptin and thus increases the adiponectin level;
• improves the density of bones, thus making them more durable and less prone to fractures and other injuries;
• no side effects. The peptide is absolutely safe, when administered at dosages that do not exceed the norm, ACE-031 does not have any side effects. Very rarely there may be headaches and discomfort at the injection site.

Dosing Details You inject 1.1ml water into the vial of ACE031 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 5 (half a unit) on the syringe each day in the morning and inject it into the muscle (Intra Muscular) at site of growth bilaterally (that is 2.5 into each side totaling 5) directly into muscle. Alternative for easier use :You inject 2.1ml water into the vial of ACE031 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 10 (1 unit) on the syringe each day in the morning and inject it into the muscle (Intra Muscular) at site of growth bilaterally (that is 5 into each side totaling 10) Directly into muscle.

How long will a vial last ? A vial should last 10 days.

Clinical Test Expectation LL-37 - Human Subjects : Antibiotic resistant infections. Immune system booster. Staphylococcus Aureus bacteria barrier. Beneficial for those who suffer with autoimmune disease, Inflammatory Bowel Disease, arthritis or Lupus. Strength - 5MG per vial

Introduction LL-37 is an antimicrobial peptide (AMP) that belongs to the cathelicidin family and serves as an alternative to antibiotics. An AMP can eliminate the bugs, regulate bacterial invasions, and control infections and inflammation. The peptide is naturally produced within the body through various tissues and circulates throughout different cells including bone marrow cells, epithelial cells and gastrointestinal tract cells. However, if the body doesn’t produce enough, it becomes vulnerable to bad bacteria, eventually causing it to accumulate pathogens and create chronic diseases and inflammation. Peptides contain amino acids that release certain proteins to focus on refining certain bodily functions. LL-37 contains approximately 12-80 amino acids with the purpose of assisting patients build immunity and fight contagious viruses.

Peptide LL-37 acts as the first line of defense when the body is suffering from injuries, infections, wounds or inflammation. Because of this, the peptide is useful in treating those suffering from tick-borne illnesses such as Lyme, RMSF, Anaplasmosis, Babesiosis and Colorado Tick Fever. Other research has shown that the peptide is effective in treating conditions such as diabetes, E. Coli, Candida Albicans, and certain types of cancer. While it’s mostly known for its anti-biofilm, the peptide also plays a critical role in regulating inflammatory molecules and contains healing properties to damaged tissues. This is especially beneficial for those who suffer with autoimmune disease, Inflammatory Bowel Disease, arthritis or Lupus.

Dosing Details You inject 2ml water into the vial of LL-37 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 30 (3 units) on the syringe each night before bed and inject it into the tummy under the skin into the fatty skin layer.

How long will a vial last ? A vial should last 7 days.

Clinical Test Expectation - Human Subjects : Reducing fibrosis in acute and chronic diseases like heart failure, lung inflammation, and the kidneys. Aids Sperm motility, testicular descent, joint health, preeclampsia, wound healing Strength - 6MG per vial

Introduction B7-33 exibits potent anti-fibrotic effects. It is under active research and investigation as a means of reducing fibrosis in acute and chronic diseases like heart failure, lung inflammation, kidney and more. In animal studies, B7-33 has reduced fibrosis by roughly 50%, leading to prolonged survival following injury and offering the first new means of treating heart failure in 20 years. It has been shown to reduce excessive scar formation following cardiac injury. It has also shown promise in the treatment of certain vascular disorders as well as preeclampsia of pregnancy.

Due to its unique structure, even though B7-33 binds to the RXFP1 receptor with greater affinity than the native H2-relaxin protein, B7-33 preferentially activates the pERK pathway over the cAMP pathway. The pERK pathway is known to play an important role in cell cycle arrest in the G1 phase and has been implicated in a number of diseases including protein-misfolding conditions like Alzheimer’s disease and Crutzfeld-Jacob disease. By arresting cell cycle progression in cells with RXFP1 receptors, B7-33 can produce a number of effects. It appears that its anti-fibrotic effects, however, are most likely mediated through the ability to stimulate RXFP1-angiotensin II type 2 receptor heterodimering, which activates pERK1/2 signaling and, eventually, leads to increased production of the collagen-degrading enzyme matrix metalloproteinase (MMP) -2. It is important that B7-33 promotes only pERK pathway activation as it is thought that cAMP activation may be responsible for some of the tumor-promoting effects seen with full-sequence H2-relaxin and not seen with B7-33

Dosing Details You inject 2ml water into the vial of B7-33 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 0.25 – 0.3 on the syringe each morning before breakfast and inject it into the tummy under the skin into the fatty skin layer.

How long will a vial last ? A vial should last 7-8 days.

Clinical Test Expectation Epithalon - Human Subjects : Anti-aging by way of increased telomerase production, which also allows replication of DNA so the body can rejuvenate old cells and grow new cells. Strength - 10MG per vial

Introduction Epitalon's primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones.

Epitalon is a synthetic peptide, telomerase activator, and putative anti-aging drug, which was identified as the putative active component of a bovine pineal gland extract known as epithalamin. Most studies on epitalon and epithalamin have been conducted by the St. Petersburg Institute of Bioregulation and Gerontology, primarily overseen by Vladimir Khavinson, in Russia.

Epitalon (also spelled Epithalon or Epithalone) is a synthetic variation of Epithalamin; a peptide secreted in the pineal gland of the brain. The pineal gland is a small pea-shaped gland sometimes referred to as ‘the third eye.’ It is more famous for secreting melatonin, the hormone associated with regulating our sleep/wake cycles.

Epitalon, often touted as ‘the fountain of youth,’ is a peptide made of four amino acids. These are alanine, glutamic acid, glycine, and aspartic acid. Peptides are short-chain amino acids that comprise two to fifty chains, which differentiate them from proteins (proteins have more than fifty chains). This peptide increases the natural production of telomerase, an enzyme that aids cells in producing telomeres, the productive parts of our DNA. The production of telomeres helps the body to produce new cells and rejuvenate the old ones.

Unfortunately, as we age, our bodies produce less and less telomerase. This affects cell replication resulting in aging. Epitalon is designed to reverse this process. Vladimir Khavinson, who studied it and conducted human and animal trials for over 35 years. These trials proved that this peptide is quite effective in fighting aging.

Epitalon is part of the new age ‘peptide therapies,’ an emerging science that uses peptides to signal different cells in the body to trigger different chemical reactions. These reactions have far-reaching effects on wound healing, muscle building, weight loss, and anti-aging.

Dosing Details You inject 2ml water into the vial of Epithalon from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 30 (3 units) on the syringe each night before bed and inject it into the tummy under the skin into the fatty skin layer.

How long will a vial last ? A vial should last 7 days.