Semax (Palmitoyl Tripeptide-1) – 10MG per vial

Clinical Test Expectation Semax - Human Subjects : Treat stroke. Transient ischemic attack. Reduce memory and cognitive disorders. Eradicate peptic ulcers. Helps with optic nerve disease. Combat depression. Anti-anxiety and sleep disorders. Prevent memory loss due to aging. Boost the immune system. Cure glaucomatous optic neuropathy. Anti-thrombosis. ADHD and learning disabilities. Gastric protection. Assists physical exertion. Improvement of pain. Helps metal toxicities. Strength - 10MG per vial

Introduction Semax is an experimental drug that was originally developed back in Russia to prevent and treat circulatory disorders. It has also been identified as a “nootropic” or “cognitive enhancer.” Also known as the Heptapeptide SEMAX (MEHFPGP), it is the analog of ACTH. It has been seen to demonstrate prolonged neuropathic activity. Historically, it has been used in patients experiencing pathologies connected to brain circulation dysfunction. This has also been suggested in literature because of its effects on carboxypeptidase which may increase physical performance and adaptation capacities in exposure due to high intensity and exercises at high doses.

This is a synthetic peptide drug developed based on the molecular structure of adrenocorticotropic hormone (ACTH).Back in Russia, Semax was initially used also to treat strokes and brain damage. This drug has also been reported to have interesting effects on animal models, reducing stress, and enhancing memory performance.

A synthetic form of the adrenocorticotropic hormone is delivered to the body through a Semax nasal spray. It works just like a regular human hormone, which counteracts stress brought by external factors from the environment. Just to give you an idea, an adrenocorticotropic hormone is a kind of hormone which is secreted by the pituitary gland that stimulates the release of cortisol coming from the adrenal gland. It regulates glucose metabolism and maintains blood pressure.

It also primes the brain for action that can reduce behaviors, like procrastination and avoidance. Semax can also induce a controlled state of mental stress, which optimizes brain function.

Semax works through chemical stimulation on the parts of the brain. These parts include:

• limbic reticular complex
• hippocampus
• body’s systems and receptors

This peptide is often prescribed for:

• Anti-thrombosis
• ADHD
• Learning
• Gastric protection
• Physical exertion
• Improvement of pain
• Metal toxicities

Dosing Details You inject 2ml water into the vial of Semax from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 25 (2.5 units / 250mcg) on the syringe each morning before breakfast and inject it into the tummy under the skin into the fatty skin layer.

How long will a vial last ? A vial should last 8 days.

Clinical Test Expectation - Human Subjects : Reducing fibrosis in acute and chronic diseases like heart failure, lung inflammation, and the kidneys. Aids Sperm motility, testicular descent, joint health, preeclampsia, wound healing Strength - 6MG per vial

Introduction B7-33 exibits potent anti-fibrotic effects. It is under active research and investigation as a means of reducing fibrosis in acute and chronic diseases like heart failure, lung inflammation, kidney and more. In animal studies, B7-33 has reduced fibrosis by roughly 50%, leading to prolonged survival following injury and offering the first new means of treating heart failure in 20 years. It has been shown to reduce excessive scar formation following cardiac injury. It has also shown promise in the treatment of certain vascular disorders as well as preeclampsia of pregnancy.

Due to its unique structure, even though B7-33 binds to the RXFP1 receptor with greater affinity than the native H2-relaxin protein, B7-33 preferentially activates the pERK pathway over the cAMP pathway. The pERK pathway is known to play an important role in cell cycle arrest in the G1 phase and has been implicated in a number of diseases including protein-misfolding conditions like Alzheimer’s disease and Crutzfeld-Jacob disease. By arresting cell cycle progression in cells with RXFP1 receptors, B7-33 can produce a number of effects. It appears that its anti-fibrotic effects, however, are most likely mediated through the ability to stimulate RXFP1-angiotensin II type 2 receptor heterodimering, which activates pERK1/2 signaling and, eventually, leads to increased production of the collagen-degrading enzyme matrix metalloproteinase (MMP) -2. It is important that B7-33 promotes only pERK pathway activation as it is thought that cAMP activation may be responsible for some of the tumor-promoting effects seen with full-sequence H2-relaxin and not seen with B7-33

Dosing Details You inject 2ml water into the vial of B7-33 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 0.25 – 0.3 on the syringe each morning before breakfast and inject it into the tummy under the skin into the fatty skin layer.

How long will a vial last ? A vial should last 7-8 days.

Clinical Test Expectation Adipotide - Human Subjects : Faster muscle mass growth, superior fat-burning power Strength - 5MG per vial

Introduction Adipotide is a synthetic peptide that possesses anti-obesity properties. this peptide particularly targets and destroys specific proteins that constitute the surface of blood vessels that support white fat (adipose) tissue hence interfering with the supply of blood to the fat cells and resulting in their adoptosis (reabsorption and metabolization). Adipotide was initially referred to as Prohibitin-TP01 (Prohibitin-Targeting Peptide 1). It is a peptidomimetic that was synthesized by American scientists as a potential therapeutic drug for obesity and its amino acid sequence is CKGGRAKDC-GG-D(KLAKLAK)2. Adipotide has a molecular formula of C111H204N36O28S2. Peptidomimetics are tiny protein like chains that imitate peptides. It is an experimental drug for weight loss. It was developed in a way that enables it to bind to two receptors, prohibitin and ANXA2 which are found in blood vessels that support white adipose tissue. In rat and monkey based experiments, Adipotide has been shown to bring about rapid weight loss in both mice and rhesus monkeys. In general, Adipotide has been observed to bring about weight loss by reducing fat tissue especially in the abdominal region), rapid metabolic changes, and decreased food intake.

Dosing Details ADIPOTIDE – Week 1 : You inject 2ml water into the vial of Adipotide from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 15 (one and a half units) on the syringe each morning before breakfast and inject it into the tummy under the skin into the fatty skin layer. A vial should last 14 days. ADIPOTIDE – Week 2 to 4 :You inject 2ml water into the vial of Adipotide from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 30 (3 units) on the syringe each morning before breakfast and inject it into the tummy under the skin into the fatty skin layer. A vial should last 7 days. Alternative Salon usage : You inject 4ml water into the vial of Adipotide from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 60 (6 units) on the syringe and inject 15 (one quarter of drawn amount) into each corner of the areas you want to be affected, for client. A vial should last 7 days.

How long will a vial last ? A vial should last 7 to 14 days

Clinical Test Expectation - Human Subjects : Lower blood sugar levels, enhance insulin secretion, improve heart, liver, and lung function while helping to slow or prevent the effects of Alzheimer’s disease. Decrease appetite by delaying gastric emptying and reducing intestinal motility. Reduce weight gain Strength - 3MG per vial

Introduction Along with helping to control blood sugar and boost weight loss, GLP-1s and SGLT-2 inhibitors seem to have other major benefits. Research has found that some drugs in these groups may lower the risk of heart disease, such as heart failure, stroke and kidney disease.

There's a class of type 2 diabetes drugs that not only improves blood sugar control but is best for weight loss. This class of drugs is commonly called glucagon-like peptide 1 (GLP-1) agonists (semaglutide). A second class of drugs that may lead to weight loss and improved blood sugar control is the sodium glucose cotransporter 2 (SGLT-2) inhibitors. These include canagliflozin (Invokana), ertugliflozin (Steglatro), dapagliflozin (Farxiga) and empagliflozin (Jardiance).

Weight loss can vary depending on which GLP-1 drug you use and your dose. Studies have found that all GLP-1 drugs can lead to weight loss of about 4.8 to 7.2 kilograms, when using liraglutide. Studies found people using semaglutide and making lifestyle changes lost about 15.3 kilograms versus 2.6 kilograms in those who didn't use the drug.

Diabetes drugs in the GLP-1 agonists class are generally taken by a shot (injection) given daily or weekly and include:

• Dulaglutide (Trulicity) (weekly)
• Exenatide extended release (Bydureon bcise) (weekly)
• Exenatide (Byetta) (twice daily)
• Semaglutide (GLP-1/Ozempic) (weekly)
• Liraglutide (Victoza, Saxenda) (daily)
• Lixisenatide (Adlyxin) (daily)
• Semaglutide (Rybelsus) (taken by mouth once daily)

These drugs mimic the action of a hormone called glucagon-like peptide 1. When blood sugar levels start to rise after someone eats, these drugs stimulate the body to produce more insulin. The extra insulin helps lower blood sugar levels.

Lower blood sugar levels are helpful for controlling type 2 diabetes. But it's not clear how the GLP-1 drugs lead to weight loss. Doctors do know that GLP-1s appear to help curb hunger. These drugs also slow the movement of food from the stomach into the small intestine. As a result, you may feel full faster and longer, so you eat less.

Along with helping to control blood sugar and boost weight loss, GLP-1s and SGLT-2 inhibitors seem to have other major benefits. Research has found that some drugs in these groups may lower the risk of heart disease, such as heart failure, stroke and kidney disease. People taking these drugs have seen their blood pressure and cholesterol levels improve. But it's not clear whether these benefits are from the drug or the weight loss.

The downside to GLP-1 drugs is that all but one has to be taken by a shot. And, like any drug, there is a risk of side effects, some serious. More common side effects often improve as you continue to take the drug for a while.

Some of the more common side effects include:

• Nausea
• Vomiting
• Diarrhea

Low blood sugar levels (hypoglycemia) are a more serious risk linked to the GLP-1 class of drugs. But the risk of low blood sugar levels often only goes up if you're also taking another drug known to lower blood sugar at the same time, such as sulfonylureas or insulin.

The GLP-1 class of drugs isn't recommended if you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia. Lab studies have linked these drugs with thyroid tumors in rats. But until more long-term studies are done, the risk to humans isn't known. They're also not recommended if you've had pancreatitis.

Dosing Details STARTING DOSE : You inject 3ml water into the vial of GLP-1 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 0.75 (3 quarters of syringe) once a week in the morning before breakfast and inject it into the tummy under the skin into the fatty skin layer. A vial should last 4 weeks.

MAINTENANCE DOSE :You inject 1ml water into the vial of GLP-1 from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out the entire vial once a week in the morning before breakfast and inject it into the tummy under the skin into the fatty skin layer. A vial should last 1 week.

How long will a vial last ? A vial should last 4 weeks on start A vial should last 1 week on maintenance

Clinical Test Expectation Epithalon - Human Subjects : Anti-aging by way of increased telomerase production, which also allows replication of DNA so the body can rejuvenate old cells and grow new cells. Strength - 10MG per vial

Introduction Epitalon's primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones.

Epitalon is a synthetic peptide, telomerase activator, and putative anti-aging drug, which was identified as the putative active component of a bovine pineal gland extract known as epithalamin. Most studies on epitalon and epithalamin have been conducted by the St. Petersburg Institute of Bioregulation and Gerontology, primarily overseen by Vladimir Khavinson, in Russia.

Epitalon (also spelled Epithalon or Epithalone) is a synthetic variation of Epithalamin; a peptide secreted in the pineal gland of the brain. The pineal gland is a small pea-shaped gland sometimes referred to as ‘the third eye.’ It is more famous for secreting melatonin, the hormone associated with regulating our sleep/wake cycles.

Epitalon, often touted as ‘the fountain of youth,’ is a peptide made of four amino acids. These are alanine, glutamic acid, glycine, and aspartic acid. Peptides are short-chain amino acids that comprise two to fifty chains, which differentiate them from proteins (proteins have more than fifty chains). This peptide increases the natural production of telomerase, an enzyme that aids cells in producing telomeres, the productive parts of our DNA. The production of telomeres helps the body to produce new cells and rejuvenate the old ones.

Unfortunately, as we age, our bodies produce less and less telomerase. This affects cell replication resulting in aging. Epitalon is designed to reverse this process. Vladimir Khavinson, who studied it and conducted human and animal trials for over 35 years. These trials proved that this peptide is quite effective in fighting aging.

Epitalon is part of the new age ‘peptide therapies,’ an emerging science that uses peptides to signal different cells in the body to trigger different chemical reactions. These reactions have far-reaching effects on wound healing, muscle building, weight loss, and anti-aging.

Dosing Details You inject 2ml water into the vial of Epithalon from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out 30 (3 units) on the syringe each night before bed and inject it into the tummy under the skin into the fatty skin layer.

How long will a vial last ? A vial should last 7 days.

Clinical Test Expectation - Tirzepatide - Human Subjects : Aids type 2 diabetis. Assist with large scale weight loss. Strength - 2MG per vial

Introduction Historically, the treatment of obesity focused almost exclusively on lifestyle-based approaches. However, evidence that diet and exercise prompt physiological counterregulatory mechanisms that limit weight reduction and impede weight maintenance has led to the realization that obesity is a complex, multicomponent metabolic disease of energy homeostasis involving central and peripheral mechanisms. Once obesity is present, those mechanisms render a return to lower weight difficult. Accordingly, several clinical guidelines now recommend treatment with antiobesity medications for people with obesity or for those with overweight and weight-related complications. Recent studies with long-acting glucagon-like peptide-1 (GLP-1) receptor agonists demonstrated that greater efficacy with acceptable safety could be achieved by targeting the pathways of endogenous nutrient-stimulated hormones. Glucose-dependent insulinotropic polypeptide (GIP), another nutrient-stimulated hormone, regulates energy balance through cell-surface receptor signaling in the brain and adipose tissue. A molecule that combines both GIP and GLP receptor agonism theoretically may lead to greater efficacy in weight reduction.

Tirzepatide is a once-weekly subcutaneous injectable peptide (approved by the Food and Drug Administration [FDA] for type 2 diabetes) engineered from the native GIP sequence, with agonist activity at both the GIP and GLP-1 receptors. Preclinical data demonstrated that the affinity of tirzepatide for GIP receptors was equal to the affinity of native GIP for GIP receptors, whereas tirzepatide bound GLP-1 receptors with affinity approximately five times weaker than native GLP-1 bound GLP-1 receptors. GIP activation appeared to act synergistically with GLP-1 receptor activation to allow greater weight reduction in humans than that achieved with GLP-1 receptor monoagonism. In phase 2 studies in people with type 2 diabetes, tirzepatide induced clinically relevant weight reduction, warranting further investigation for the treatment of obesity. The present trial, SURMOUNT-1, evaluated the efficacy and safety of tirzepatide in adults with obesity or overweight who did not have diabetes with great success

Dosing Details You inject 1ml water into the vial of Tirzepatide from the water vial. 1 full syringe is 1ml. You then wait for the vial powder content to dissolve ON ITS OWN. DO NOT SHAKE THE VIAL TO MIX POWDER. Once dissolved and clear in colour you draw out the entire vial and inject it into the tummy under the skin into the fatty skin layer. A vial should last 1 usage once a week.

How long will a vial last ? A vial should last 7 days.